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mu·ta·tion [mju:ˈteɪʃən] ISIM
- mutation
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- mutation
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chromosomal mutation ISIM
- chromosomal mutation
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mutation event
- mutation event
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germline mutation ISIM
- germline mutation
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mutation rate
- mutation rate
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genomic mutation ISIM
- genomic mutation
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nonsense mutation ISIM
- nonsense mutation
- Unsinnsmutation (vorzeitiges Stoppcodon)
back mutation ISIM
- back mutation
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somatic mutation [səˌmætɪkmjuːˈteɪʃn] ISIM
- somatic mutation
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point mutation ISIM
- point mutation
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Tek dilli örnekler (PONS yazı işleri tarafından onaylanmamıştır)
To date 174 out of the 175 studied drug targets so far have been recorded with somatic mutations.
www.digitaljournal.com To date 287 out of the 289 studied drug targets so far have been recorded with somatic mutations.
www.digitaljournal.com More recent investigations have resulted in the development of software tools especially optimized for the detection of somatic mutations from multiple tissue samples.
en.wikipedia.org Somatic mutation leading to mosaicism is prevalent in the beginning and end stages of human life.
en.wikipedia.org Further, cancer tissues with high age acceleration tend to have fewer somatic mutations than those with low age acceleration.
en.wikipedia.org İnternetten örnekler (PONS yazı işleri tarafından onaylanmamıştır)
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www.uni-muenchen.de It occurs in approximately 75,000 new cancer cases per annum and is the most frequent mutation, in which p53 is deactivated by thermodynamic destabilization — all because a single building block of the protein is replaced.
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Sie kommt in etwa 75.000 neu an Krebs erkrankten Menschen pro Jahr vor und ist die häufigste Veränderung, bei der p53 durch thermodynamische Destabilisierung inaktiviert wird. Und zwar durch den Austausch eines einzigen Bausteins des Proteins.
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www.uni-muenchen.de We now know that every malignant tumor is the result of underlying genetic mutations that affect several different classes of genes.
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Mittlerweile weiß man, dass jeder bösartigen Tumorerkrankung genetische Veränderungen zugrunde liegen, die mehrere Klassen von Genen betreffen.
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www.uni-muenchen.de Fatal mutations to the p53 gene are found in nearly half of all tumor cases in humans, and the associated p53 protein is therefore no longer able to fulfill its duties as “guardian of the genome.”
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Bei etwa der Hälfte der menschlichen Tumore finden sich aber fatale Veränderungen im p53-Gen. Das zugehörige p53-Protein kann dann seinen Aufgaben als „Wächter des Genoms“ nicht mehr nachkommen.
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frauenklinik-cvk.charite.de Focus of the ward is besides endoscopical surgeries (so-called laparoscopy resp. minimal invasive surgery) the care of patients after laser therapy for treatment of malign mutations of the outer genitals (labia and vagina).
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Schwerpunkt der Station ist neben endoskopischen Eingriffen (sogenannte Bauchspiegelung bzw. minimal-invasive Chirurgie) die Betreuung von Patientinnen nach Lasertherapie zur Behandlung von bösartigen Veränderungen der äußeren Genitale (Schamlippen und Scheide).
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www.dkfz.de The number of mutations increases with the age of the affected individuals.
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Die Anzahl der genetischen Veränderungen stieg mit dem Alter der Betroffenen.
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